Simvastatin attenuates neutrophil recruitment in one-lung ventilation model in rats
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چکیده
منابع مشابه
Simvastatin attenuates neutrophil recruitment in one-lung ventilation model in rats.
PURPOSE To investigate the anti-inflammatory effects of simvastatin in rats undergoing one-lung ventilation (OLV) followed by lung re-expansion. METHODS Male Wistar rats (n=30) were submitted to 1-h OLV followed by 1-h lung re-expansion. Treated group received simvastatin (40 mg/kg for 21 days) previous to OLV protocol. Control group received no treatment or surgical/ventilation interventions...
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PURPOSE To investigate the morphological and functional behavior of neutrophils during and after one-lung ventilation (OLV). METHODS We utilized an OLV rat model system and performed 3 hours of OLV followed by either re-expansion (RE) and 30 minutes of two-lung ventilation (TLV) (RE group), only two-lung ventilation (TLV group), or only OLV (OLV group). Cytoskeletal rearrangements of circulat...
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The application of the independent lung ventilation (ILV) in adults has been described by Carlon and co-workers in 1978 and subsequently by other investigators. In 1983 Hedenstierna and coworkers using a bilumen tube suitable for prolonged intubation, and two Servo Ventilator 900 B (Siemens) adapted for synchronization, treated a wide range of clinical conditions. Following this experience, the...
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Objective: The purpose of this study was to investigate the effects of two different ventilation modes: Volume-Controlled Ventilation (VCV) with Lung Recruitment Maneuvers (LRM) vs. PressureControlled Ventilation (PCV) with LRM during One-Lung Ventilation (OLV) in patients undergoing thoracoscopic lobectomy. Methods: Position of Double-lumen endobronchial tube (DLT) was assessed by a fiberoptic...
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ژورنال
عنوان ژورنال: Acta Cirurgica Brasileira
سال: 2013
ISSN: 0102-8650
DOI: 10.1590/s0102-86502013000400003